84-4423-27　IL9R (Interleukin 9 Receptor, CD129, IL9-R, Cluster Of Differentiation 129) 200ul　363725

特徴

• Interleukin 9 receptor (IL9R) also known as CD129 is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9).
• The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines.
• The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses.
• This gene is located at the pseudoautosomal regions of X and Y chromosomes.
• Genetic studies suggested an association of this gene with the development of asthma.
• Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described.
• Alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- GQKA GAFTCLSNSI YRIDCHWSAP ELGQESRAWL LFTSNQVTEI KHKCTFWDSM CTLVLPKEEV FLPFDNFTIT LHRCIMGQEQ VSLVDSQYLP RRHIKLDPPS DLQSNVSSGR CVLTWGINLA LEPLITSLSY ELAFKRQEEA WEARHKDRIV GVTWLILEAV ELNPGSIYEA RLRVQMTLES YEDKTEGEYY KSHWSEWSQP VSFPSPQ
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.