IL2RGis located on the surface of immature blood-forming cells in bone marrow.
It has one end outside the cell like an antenna and the other end inside to transmit signals to the cell's nucleus.
The common gamma chain partners with other proteins to direct blood-forming cells to form lymphocytes (a type of white blood cell).
The receptor also directs the growth and maturation of lymphocyte subtypes: T cells, B cells, and natural killer cells.
These cells kill viruses, make antibodies, and help regulate the entire immune system.X-linked severe combined immunodeficiency is caused by mutations in the IL2RG gene.
More than 200 different mutations in the IL2RG gene have been identified in people with X-linked severe combined immunodeficiency (SCID).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-3ug/mlImmunohistochemistry (Paraffin): 5-30ug/mlImmunocytochemistry: 5-30ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol
Specificity：Recognizes mouse IL2Rg
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to aa23-A263 of mouse IL2Rg, expressed in E. coli
