84-4422-97　IL2Ra (Interleukin 2 Receptor Alpha, CD25, IL2R-a, IL2-RA, IDDM10, IL2R, TCGFR, p55, TAC antigen) 200ul　363696

特徴

• CD25 is the alpha chain of the IL-2 receptor.
• It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2.
• CD25 expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes.
• Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.
• Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.
• Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is currently unknown.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- EACHDDPPS LRNAMFKVFR YEVGTMINCD CKTGFRRVSA VMRCVGDSSH SAWENRCFCN STSPAKNQVK QVTPAPEEHR EKKHTDAQNQ TQPPEEADLP GHCEEPPPWE HEREPLKRVY HFTLGQTVHY QCAQGFRALQ TSPAESTCMM INGELRWTRP RLKCIREGEH GQASDDAEPQ ESTEAPPGSG TFLPTRMAGT TNFQKPTDEI ATLDTFIFTT EYQ
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.