Interleukin-29 (IL-29) is a protein of the helical cytokine family and is a type III interferon.
It is also known as IFNlambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon.
IL-29 is a cytokine distantly related to type I interferons and the IL-10 family.
This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13.
Expression of the cytokines encoded by the three genes can be induced by viral infection.
All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.