84-4422-76　IL1z (Interleukin 1 Zeta, IL1F7, IL37, FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1H4, IL1RP1, Interleukin 37, Interleukin-1-Related Protein, Interleukin 1 Family, Member 7) 200ul　363675

特徴

• IL1zis a member of the interleukin 1 cytokine family.
• This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp).
• This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18.
• This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
• Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node.
• Isoform D and isoform E were found only in testis and bone marrow.
• Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-VHTSP KVKNLNPKKF SIHDQDHKVL VLDSGNLIAV PDKNYIRPEI FFALASSLSS ASAEKGSPIL LGVSKGEFCL YCDKDKGQSH PSLQLKKEKL MKLAAQKESA RRPFIFYRAQ VGSWNMLESA AHPGWFICTS CNCNEPVGVT DKFENRKHIE FSFQPVCKAE MSPSEVSD
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.