IL1RAPL2 is a member of the interleukin 1 receptor family.
This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1).
This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation.
The 307aa cytoplasmic tail of the predicted 686aa protein contains an additional 120 to 130 residues beyond the THD, like IL1R8 (IL1RAPL1) but unlike other IL1Rs.
Evolutionary sequence analysis suggested that IL1R8 and IL1R9 probably form a functionally distinct subset of orphan receptors in the IL1R superfamily.
Northern blot analysis revealed expression of a 5.5-kb transcript in fetal brain.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human IL1RAPL2.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ser161-Thr330 of human IL1RAPL2, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
