IL1RAPL1 is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins.
It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2).
This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation.
Deletions and mutations in this gene were found in patients with mental retardation.
This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.
This gene encodes a 696aa protein that has homology to interleukin-1 receptor accessory proteins (IL1RAP).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human IL1RAPL1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ser113-Asp276 of human IL1RAPL1, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
