84-4422-68　IL1R1 (Interleukin 1 Receptor Type I, CD121a, CD121-A, IL1-R1, IL1R, IL1RA, P80, CD121 Antigen-Like Family Member A, Interleukin-1 Receptor Alpha) 200ul　363667

特徴

• Interleukin 1 Receptor Type I is a cytokine receptor that belongs to the interleukin-1 receptor family.
• This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA).
• It is an important mediator involved in many cytokine induced immune and inflammatory responses.
• This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12
• Both human IL1R gene and  mouse gene containing a single membrane-spanning segment, a large cytoplasmic region, and an extracellular, IL1-binding portion composed of 3 immunoglobulin-like domains.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- L EIDVCTEYPN QIVLFLSVNE IDIRKCPLTP NKMHGDTIIW YKNDSKTPIS ADRDSRIHQQ NEHLWFVPAK VEDSGYYYCI VRNSTYCLKT KVTVTVLEND PGLCYSTQAT FPQRLHIAGD GSLVCPYVSY FKDENNELPE VQWYKNCKPL LLDNVSFFGV KDKLLVRNVA EEHRGDYICR MSYTFRGKQY PVTRVIQFIT IDENKRDRPV ILSPRNETIE ADPGSMIQLI CNVTGQFSDL VYWKWNGSEI EWNDPFLAED YQFVEHPSTK RKYTLITTLN ISEVKSQFYR YPFICVVKNT NIFESAHVQL IYPVPDFK
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.