84-4422-45　［受注停止］IL17C (Interleukin 17C, Cytokine CX2) 200ul　363644

特徴

• Interleukin 17C is a T cell-derived cytokine that shares the sequence similarity with IL17.
• This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line.
• The expression of this cytokine was found to be restricted to activated T cells.
• Northern blot analysis detected an 800-bp IL17B mRNA in adult pancreas, small intestine, and stomach, whereas IL17C mRNA was not detected in several adult tissues.
• No expression of IL17B or IL17C mRNA was found in activated T cells.
• The authors found that IL17B and IL17C differ from IL17 in their patterns of expression and biologic activities.
• These findings, coupled with the lack of interaction with the known IL17 receptor, suggested an expanded role for the IL17 family in the proinflammatory immune response.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- CYSAE ELPLGQAPPH LLARGAKWGQ ALPVALVSSL EAASHRGRHE RPSATTQCPV LRPEEVLEAD THQRSISPWR YRVDTDEDRY PQKLAFAECL CRGCIDARTG RETAALNSVR LLQSLLVLRR RPCSRDGSGL PTPGAFAFHT EFIHVPV
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.