IL-16 is constitutively expressed by both CD4+ and CD8+ T cells.
Airway epithelium from asthmatics, eosinophils, and mast cells also produce IL-16, albeit only after stimulation
In lymphocytes, IL-16 is generated as a precursor molecule which is enzymatically cleaved following stimulation with T-cell mitogens.
IL-16 is a proinflammatory and immunomodulatory cytokine.
It is a potent chemoattractant for all CD4+ cells including T cells, monocytes, and eosinophils and, as such, has been identified at inflammatory sites characterized by infiltrating CD4+ cells.In addition to cell motility, IL-16 induces cell cycle progression and cytokine synthesis in CD4+ T cells.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：bovine
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes bovine IL16.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Bo
Immunogen：Recombinant protein corresponding to Ser508-Pro627 of bovine IL16, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
