84-4422-34　IL13 (Interleukin 13, ALRH, BHR1, P600, IL-13, NC30) 200ul　363633

特徴

• Interleukin 13 (IL-13) is produced primarily by activated T lymphocytes.
• It shows approximately 30%aa sequence identity with IL-4 and shares many biological properties with IL-4.
• IL-13 has multiple effects on the differentiation and functions of monocytes/macrophages.
• It can suppress the cytotoxic functions of monocytes/macrophages and the production of proinflammatory cytokines by monocytes/macrophages.
• The biological effects of IL-13 are mediated by specific high-affinity cell surface receptor complexes.
• The functional IL-13 receptor complex has been shown to consist of the low-affinity IL-13 receptor alpha chain and the IL-4 receptor alpha subunit (IL-4 Ralpha).
• This IL-13 receptor complex may also serve as an alternate high-affinity IL-4 receptor complex in IL-4 responsive cells that lack the gamma chain.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-LTCLGG FASPGPVPPS TALRELIEEL VNITQNQKAP LCNGSMVWSI NLTAGMYCAA LESLINVSGC SAIEKTQRML SGFCPHKVSA GQFSSLHVRD TKIEVAQFVK DLLLHLKKLF REGRFN
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.