IL-11 receptor is a member of the hematopoietic cytokine receptor family.
This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.
Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
This receptor was found to be a 422aa protein containing a signal peptide followed by extracellular, transmembrane, and cytoplasmic domains.
The extracellular region has a 2-domain structure homologous to those of the receptors for IL6R and ciliary neurotrophic factor (CNTFR), an immunoglobulin-like domain and a cytokine receptor-like domain.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes rat IL11Ra.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to Thr24-Ala371 of rat IL11Ra, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
