84-4420-73 HMG17 (High Mobility Group Protein 17, HMGN2, High mobility group nucleosome-binding domain-containing protein 2, Non-histone chromosomal protein HMG-17) 200ul 363473
84-4420-73 HMG17 (High Mobility Group Protein 17, HMGN2, High mobility group nucleosome-binding domain-containing protein 2, Non-histone chromosomal protein HMG-17) 200ul 363473
High mobility group nucleosomal binding protein 2(HMGN2)is an evolutionarily conserved non-histone protein found in the nuclei of higher eukaryotes.
The protein is thought to be involved in the regulation of chromatin structure and transcriptional activation of mammalian genes.
Lehtonen et al (1998) have reported that the HMGN2 protein shows developmental regulation during organogenesis in mice.
Gene expression is found in differentiating tissue regions and appears to be down-regulated in mature structures.
Mohamed et al (2001) have reported that HMGN2 protein is a constitutive component of mouse oocytes and embryonic chromatin and maintains the timing of early embryonic development in the mouse.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human HMG17.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Pro2-Gln81 of human HMG17, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.