Helicase-like transcription factor is a member of the SWI/SNF family.
Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.
The encoded protein contains a RING finger DNA binding motif.
Two transcript variants encoding the same protein have been found for this gene.
However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.Possesses intrinsic ATP-dependent nucleosome-remodeling activity.
This activity may be required for transcriptional activation or repression of specific target promoters.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human HLTF.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ala837-Lys996 of human HLTF, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
