The N-methyl-D-aspartate (NMDA) receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning.
Functional NMDA receptors appear to be composed (minimally) of an invariant subunit (NMDAR1) and 1 of several variable subunits.
Each of the variable subunits exhibits a distinct distribution in the adult brain.
For example, postnatally, NMDA receptors containing the NMDAR2B subunit are primarily localized to the hippocampus and forebrain.
The sequence of the predicted 1484aa human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human GRIN2B.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Ile35-Asp557 of human GRIN2B, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.