84-4419-48　GPI (Glucose 8 Phosphate Isomerase , AMF, NLK, PHI, SA36, Phosphoglucose Isomerase, Autocrine motility factor, Neuroleukin, Phosphohexose isomerase, Sperm antigen 36) 200ul　363349

特徴

• Glucose-6-phosphate isomerase has an essential function in both catabolic glycolysis and anabolic gluconeogenesis and is universally distributed among Eukaryotes, Bacteria, and some Archaea.GPI is expressed by the corpus luteum on days 6–9 of pregnancy, the time at which implantation-promoting activity has been found in corpora lutea.
• Passive immunization against GPI reduced the number of implantation sites in pregnant ferrets in a dose-dependent manner.
• GPI is a multifunctional protein.
• Although first identified for its role in glycolysis, GPI has since been implicated in neural growth, lymphocyte maturation, and metastasis.
• This study demonstrates a previously uncharacterized function of this protein that may represent the natural motility-stimulating activity that has been co-opted by tumor cells.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-TKSGAR VDYQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRNGL HHKILLANFL AQTEALMKGK SPEEARKELQ AAGKSPEELE KLLPHKVFEG NRPTNSIVFT KLTPFILGAL IAMYEHKIFV QGIIWDINSF DQWGVELGKQ LAKKIEPELD GSSAVTSHDS STNGLIGFIK LQRDTKID
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.