84-4419-41　GP5 (Glycoprotein V, Platelet, CD42-D, CD42d) 200ul　363342

特徴

• Glycoprotein V (platelet) (GP5) also known as CD42d (Cluster of Differentiation 42d), is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis
• The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA) and a beta chain (GP1BB), that are linked by disulfide bonds.
• The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9) and GP5.
• Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorder.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QPFP CPPACKCVFR DAAQCSGGDV ARISALGLPT NLTHILLFGM GRGVLQSQSF SGMTVLQRLM ISDSHISAVA PGTFSDLIKL KTLRLSRNKI THLPGALLDK MVLLEQLFLD HNALRGIDQN MFQKLVNLQE LALNQNQLDF LPASLFTNLE NLKLLDLSGN NLTHLPKGLL GAQAKLERLL LHSNRLVSLD SGLLNSLGAL TELQFHRNHI RSIAPGAFDR LP
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.