Guanine nucleotide-binding protein G(z) subunit alpha is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems.
This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids.
By in situ hybridization, Wilkie et al.
(1992) demonstrated that the GNAZ gene is located in band 22q11.
By the analysis of RFLVs in an interspecific backcross, they showed that the corresponding gene is located on mouse chromosome 10.
Budarf et al.
(1991) further narrowed the localization to 22q11.2 by fluorescence in situ hybridization on reverse banded metaphase chromosomes.
They confirmed the localization by means of a regional mapping panel of somatic cell hybrids.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human GNaZ.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Gly2-Val219 human GNaZ, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
