The growth hormone releasing hormone receptor (GHRHR) is a G-protein coupled receptor which binds growth hormone releasing hormone.This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone.
Binding of this hormone to the receptor leads to synthesis and release of growth hormone.
Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.
Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date.Receptor for GRF, coupled to G proteins which activate adenylyl cyclase.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human GHRHR.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to His23-Lys130 of human GHRHR, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
