84-4418-31　GATA4 (GATA Binding Protein 4, Transcription factor GATA-4) 200ul　363233

特徴

• Transcription factor GATA-4 is a member of the GATA family of zinc-finger transcription factors.
• Members of this family recognize the GATA motif which is present in the promoters of many genes.
• This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function.
• Mutations in this gene have been associated with cardiac septal defects.
• A fourth member of the GATA-binding family, GATA4, is expressed in adult vertebrate heart, gut epithelium, and gonads.
• During fetal development, GATA4 is expressed in yolk sac endoderm and cells involved in heart formation.
• This factor may regulate genes critical for myocardial differentiation and function, including troponin C, cardiac alpha-myosin heavy chain (MYH6), and brain-type natriuretic factor.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-RHPNLDMFDD FSEGRECVNC GAMSTPLWRR DGTGHYLCNA CGLYHKMNGI NRPLIKPQRR LSASRRVGLS CANCQTTTTT LWRRNAEGEP VCNACGLYMK LHGVPRPLAM RKEGIQTRKR KPKNLNKSKT PAAPSGSESL PPASGASSNS SNATTSSSEE MRPIKTEPGL SSHYGHSSSV SQTFSVSAMS GHGPSIHPVL SALKLSPQGY ASPVSQSPQT SSKQDSWNSL VLADSHGDII TA
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.