84-4418-28　GATA1 (GATA Binding Protein 1, ERYF1, GF1, NFE1, Globin Transcription Factor 1, Erythroid transcription factor, NF-E1 DNA-binding protein) 200ul　363230

特徴

• GATA1 is an important transcription factor involved in cell growth and cancer.
• The protein belongs to the GATA family of transcription factors.
• The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin.
• Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia
• It is essential for erythroid (red blood cell) and megakaryocytic (platelet producing cell) development and mice without GATA1 die as embryos.
• It helps transcribe the alpha-spectrin structural protein which is critical for the shape of red blood cells.It has been found to enhance the transcription rates by up to 100 times in humans.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- P ALPSSLPVPN SAYGGPDFSS TFFSPTGSPL NSAAYSSPKL RGTLPLPPCE ARECVNCGAT ATPLWRRDRT GHYLCNACGL YHKMNGQNRP LIRPKKRLIV SKRAGTQCTN CQTTTTTLWR RNASGDPVCN ACGLYYKLHQ VNRPLTMRKD GIQTRNRKAS GKGKKKRGSS LGGTGAAEGP AGGFMVVAGG SGSGNCGEVA SGLTLGPPGT AHLYQGLGPV VLSGPVSHLM PFPG
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.