84-4418-18　GAP43 (Growth Associated Protein 43, F1, B-50, PP46, Neuron Growth-Associated Protein 43, Neuromodulin, Axonal Membrane Protein GAP-43, Protein F1, Calmodulin-Binding Protein P-57, Neural Phosphoprotein B-50) 200ul　363220

特徴

• Growth-associated protein 43, GAP-43 is a nervous tissue specific protein which is highly expressed in neurons during development and nerve regeneration.
• It has been implicated in neurite outgrowth, long-term potentiation, signal transduction, and neurotransmitter release.
• It is also a substrate of Protein Kinase C.
• Group of developmentally regulated polypeptides thought to be critical for the formation of neural circuitry.
• The acidic membrane phosphoprotein GAP 43 is synthesised and transported down regenerating and developing axons, pp46 localised in growth cone membranes during embryogenesis, B 50 in mature presynaptic membranes in the regulation of phosphotidylinositol turnover and F1 in the hippocampus during long-term potentiation, are now all known to be the same protein.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- TKQ VEKNDEDQKI QDGVKPEDK AHKAATKIQA SFRGHITRKK LKGEKKGDAPAAEAEAKEKD DAPVADGVEK KEGDGSATTD AAPATSPKAE EPSKAGDAPS EEKKGEGDAAPSEEKAGSAE TESAAKATTD NSPSSKAEDG PAKEEPKQAD VPAAVTDAAA TTPAAEDAATKAAQPPTETA ESSQAEEEKD AVDEAKPKES ARQDEGKEDP EADQEHA
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.