Galectin-9 (Gal-9) is a member of animal lectins that have an affinity to beta-galactosides.
Gal-9 was first cloned from tumor tissues of Hodgkin’s disease that is frequently characterized by eosinophilia.
Galectins exhibit various biological functions, such as cell aggregation and adhesion, proliferation,cell death, modulation of inflammation and metastasis.
First, Gal-9/ecalectin was identified as a potent T cellderived eosinophil chemoattractant (ECA)
Gal-9 exhibits ECA activity in vitro and in vivo, activates eosinophils, and influences eosinophil survival.
It requires divalent galactoside- binding activity but not its linker peptide to exhibit its functions, and some matrix metalloproteinases are involved in the release.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human GAL9.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Met1-Thr355 of human GAL9, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
