84-4417-72　FUT3 (Fucosyltransferase 3, CD174, FUT3, FT3B, LE, Les, FucT-III, Lewis FT, Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group, Blood group Lewis alpha-4-fucosyltransferase) 200ul　363174

特徴

• The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids.
• The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion.
• They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype.
• This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis.
• It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.
• Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes.
• Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap