Ferritin heavy chain is a heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes.
It is composed of 24 subunits of the heavy and light ferritin chains.
Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues.
A major function of ferritin is the storage of iron in a soluble and nontoxic state.
Defects in ferritin proteins are associated with several neurodegenerative diseases.
This gene has multiple pseudogenes.
Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
The functionality of the gene was demonstrated by the fact that both transient transfectants and stable transformants of mouse fibroblasts actively transcribed human ferritin heavy-chain mRNA.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human FTH.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Met1-Ser183 of human FTH, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
