The Flt3l is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors.
It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells
FLT3L is crucial for steady-state pDC and cDC development.
A lack of FLT3L results in low levels of DCs.Flt3 ligand (FL) is a hematopoietic four helical bundle cytokine.
It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1).
In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-2ug/mlImmunohistochemistry (Paraffin): 5-20ug/mlImmunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol
Specificity:Recognizes mouse Flt3L
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Mo
Immunogen:Recombinant protein corresponding to aa27-189 of mouse Flt3L, expressed in E. coli