Leucine-rich repeat transmembrane protein FLRT2 is a member of the fibronectin leucine rich transmembrane protein (FLRT) family.
FLRT family members may function in cell adhesion and/or receptor signalling.
Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.
The full-length FLRT2 coding sequence encodes a predicted 660aa protein containing a putative N-terminal signal sequence, 10 leucine-rich repeats (LRRs) flanked by N- and C-terminal cysteine-rich regions, a fibronectin-/collagen-like domain, a transmembrane domain, and an intracellular C-terminal tail.
FLRT2 has 5 potential N-glycosylation sites in its extracellular region.
FLRT2 shares 44% aa sequence identity with FLRT3 and 41% identity with FLRT1.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human FLRT2.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ser300-Ser51 of human FLRT2, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
