84-4417-21　［受注停止］FKBP7 (FK506 Binding Protein 7, FKBP23, Rotamase, 23kD FK506-binding protein, Peptidyl-prolyl cis-trans isomerase FKBP7) 200ul　363123

特徴

• FK506 Binding Protein 7 belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family.
• Members of this family exhibit PPIase activity and function as molecular chaperones.
• A similar protein in mouse is located in the endoplasmic reticulum and binds calcium.
• The deduced 218aa protein contains an N-terminal hydrophobic signal sequence, a PPIase motif, 2 EF-hand domains, and 2 putative N-glycosylation sites.
• The calculated molecular mass is about 22kD, but becomes 33kD following cleavage of the signal sequence.
• Northern blot analysis detected expression of a 0.9-kb transcript predominantly in heart, lung, and testis.
• Immunolocalization in transfected COS-7 cells revealed a perinuclear distribution that overlapped that of an endoplasmic reticulum resident protein.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QRQKKEE STEEVKIEVL HRPENCSKTS KKGDLLNAHY DGYLAKDGSK FYCSRTQNEG HPKWFVLGVG QVIKGLDIAM TDMCPGEKRK VVIPPSFAYG KEGYAEGKIP PDATLIFEIE LYAVTKGPRS IETFKQIDMD NDRQLSKAEI NLYLQREFEK DEKPRDKSYQ DAVLEDIFKK NDHDGDGFIS PKEYNVY
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.