84-4417-13　FGL2 (Fibrinogen Like Protein 2, T49, PT49, Fibroleukin) 200ul　363115

特徴

• FGL2 is a 439aa secreted protein that is similar to the Beta- and Gamma-chains of fibrinogen.
• The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED).
• The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds
• This protein may play a role in physiologic functions at mucosal sites.Fgl2 is a protein that exhibits pleiotropic effects within the body and is an important immune regulator of both innate and adaptive responses.
• The protein exists as both a type II transmembrane protein found on the surface of macrophages and endothelial cells and can be constitutively secreted by both CD4+ and CD8+ T cells.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- V EEHNLTEGLE DASAQAACPA RLEGSGRCEG SQCPFQLTLP TLTIQLPRQL GSMEEVLKEV RTLKEAVDSL KKSCQDCKLQ ADDHRDPGGN GGNGAETAED SRVQELESQV NKLSSELKNA KDQIQGLQGR LETLHLVNMN NIENYVDNKV ANLTVVVNSL DGKCSKCPSQ EHMQSQPVQH LIYKDCSDHY VLGRRSSGAY RVTPDHRNSS FEVYCDMETM GGGWTVLQAR LDGSTNFTRE WKDYKAGFGN LEREFWLGND KIHLLTKSKE MILRIDLEDF NGLTLYALYD QFYVANEFLK YRLHIGNYNG TAGDALRFSR HYNHDLRFFT TPDRDNDRYP SGNCGLYYSS GWWFDSCLSA NLNGKYYHQK YKGVRNGIFW GTWPGINQAQ PGGYKSSFKQ AKMMIRPKNF KP
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.