84-4416-89　［受注停止］FES (Feline Sarcoma Oncogene, FPS, Oncogene FES, Feline Sarcoma Virus, c-Fes/Fps Protein, Feline sarcoma/Fujinami avian sarcoma oncogene homolog) 200ul　363092

特徴

• FES encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities.
• The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation.
• Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling.
• Alternative splicing results in multiple variants encoding different isoforms
• The FES protooncogene encodes a cytoplasmic protein tyrosine kinase implicated in growth factor and cytokine receptor signaling.
• It is involved myelopoiesis and plays a role in regulating the innate immune response.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- LD NLYRLEGEGF PSIPLLIDHL LSTQQPLTKK SGVVLHRAVP KDKWVLNHED LVLGEQIGRG NFGEVFSGRL RADNTLVAVK SCRETLPPDL KAKFLQEARI LKQYSHPNIV RLIGVCTQKQ PIYIVMELVQ GGDFLTFLRT EGARLRVKTL LQMVGDAAAG MEYLESKCCI HRDLAARNCL VTEKNVLKIS DFGMSREEAD GVYAASGGLR QVPVKWTAPE ALNYGRYSSE SDVWSFGILL WETFSLGASP YPNLSN
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.