84-4416-80 FcaR (Fc Fragment Of IgA Receptor, CD89, FcaRI, Receptor I For The Fc Region Of Immunoglobulin A, IgA Fc receptor, Immunoglobulin alpha Fc receptor) 200ul 363083
84-4416-80 FcaR (Fc Fragment Of IgA Receptor, CD89, FcaRI, Receptor I For The Fc Region Of Immunoglobulin A, IgA Fc receptor, Immunoglobulin alpha Fc receptor) 200ul 363083
Only one Fc receptor belongs to the FcalphaR subgroup, which is called Fcalpha RI (or CD89).
Fcalpha RI is found on the surface of neutrophils, eosinophils, monocytes, some macrophages (including Kupffer cells), and some dendritic cells.
It is composed of two extracellular Ig-like domains, and is a member of both the immunoglobulin superfamily and the multi-chain immune recognition receptor (MIRR) family.
It signals by associating with two FcR gamma signaling chains
Another receptor can also bind IgA, although it has higher affinity for another antibody called IgM.
This receptor is called the Fc-alpha/mu receptor (Fcalpha /muR) and is a type I transmembrane protein.
With one Ig-like domain in its extracellular portion, this Fc receptor is also a member of the immunoglobulin superfamily.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human FcaR.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Gln22-Asn227 of human FcaR, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.