84-4416-64　FATP5 (Fatty Acid Protein 5, SLC27A5, ACSB, ACSVL6, FACVL3, VLACSR, BACS, VLCSH2, Fatty Acid Coenzyme A Ligase Very Long Chain 3, Solute Carrier Family 27 Member 5, Bile Acyl CoA Synthetase) 200ul　363067

特徴

• Very long chain fatty acid synthetase (VLACS, or SLC27A2), an enzyme whose function is presumed missing in ALD, is highly expressed in liver and kidney, but is expressed at much lower levels in brain.
• However, brain contains high amounts of VLCFA and is the organ most affected in ALD.
• In an attempt to isolate a VLACS isoform with a different tissue distribution, Berger et al.
• (1998) used degenerate PCR to clone a mouse cDNA and a partial human cDNA encoding a VLACS-related protein, termed VLACSR.
• VLACSR is 43% identical to mouse VLACS and 37% identical to mouse FATP.
• Northern blot analysis of mouse tissues revealed that a 2.6-kb VLACSR mRNA was highly abundant in liver.
• Smaller VLACSR transcripts were present at low levels in brain, lung, testis, spleen, and skeletal muscle.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.