Ileal lipid-binding protein (symbolized ILBP by Birkenmeier et al., 1994) is a member of a family of intracellular fatty acid, retinoid, and bile acid-binding proteins.
This protein, with 128 residues in the mouse, is expressed only in differentiated members of the enterocyte lineage located in ileal villi.
ILBP binds conjugated and unconjugated bile salts and appears to function as the cytosolic receptor for bile acids that have undergone sodium-dependent active transport by the ileal bile acid transporter (IBAT).
Birkenmeier et al.
(1994) mapped the Illbp gene to mouse chromosome 11 by interspecific backcross analysis.
The nearest locus in the mouse is Csfgm, which in the human genome is located on 5q31.1 (CSF2), suggesting that the human homolog of mouse Illbp may reside on human 5q.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human FABP6.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Met1-Ala128 of human FABP6, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
