AP2 (adipocyte Protein 2) is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages.
aP2 is also called fatty acid binding protein 4 (FABP4).
Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease,diabetes, asthma, obesity, and fatty liver disease
Baxa et al.
(1989) purified human adipocyte FABP (called H-ALBP by them) from normal subcutaneous adipose tissue.
The 15kD protein composed about 1% of total cytosolic protein in human adipose tissue.
They also cloned a full-length cDNA that encodes a predicted 132aa polypeptide.
Baxa et al.
(1989) also identified a consensus tyrosyl kinase phosphorylation site.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:chicken
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Specificity:Recognizes chicken FABP4.
Isotype:IgY
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Ch
Immunogen:Recombinant protein corresponding to Met1-Ser125 of chicken FABP4 expressed in E. coli.