Prostaglandin E receptor 3, also known as EP3, is a prostaglandin receptor, The receptor is a member of the G-protein coupled receptor family.
It is one of four receptors identified for prostaglandin E2 (PGE2).
This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities.
In the stomach, it inhibits gastric acid secretions.
Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli.Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry: 5-20ug/mlImmunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% Proclin-300, 50% glycerol.
Specificity：Recognizes human EP3. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to Asn217-Arg390 of human EP3, expressed in E. coli.
