Prostaglandin E2 receptor (53kD), also known as EP2, is a prostaglandin receptor for prostaglandin E2.
The receptor is a G-protein coupled receptor, which activates the G protein Gs
Prostaglandin E2 (PGE2), one of various oxygenated metabolites of arachidonic acid, produces a broad range of biologic actions in diverse tissues.
Not only are PGE2 and thromboxane A2 structurally related, but their receptors are also homologous.
Taketo et al.
(1994) cloned mouse cDNA sequences for PGE2 receptor subtypes EP2 (PTGER2) and EP3 (PTGER3).Prostanoid receptors of the EP1, EP2, EP3, and EP4 types cloned in the mouse and/or human were reviewed by Coleman et al.
(1994).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100ELISA: 1:100-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human EP2.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ala155-Gln355 of human EP2, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
