The innate immune system includes antimicrobial peptides that protect multicellular organisms from a diverse spectrum of microorganisms.
beta-Defensins comprise one important family of mammalian antimicrobial peptides.
Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms.
DEFb126 is secreted and is a member of the beta defensin protein family.
Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.
The encoded protein is highly similar to an epididymal-specific secretory protein (ESP13.2) from cynomolgus monkey.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human DEFb126.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Asn21-Gly111 of human DEFb126, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
