Neutrophilic polymorphonuclear leukocytes contain specialized azurophil granules whose contents, including the serine proteases cathepsin G and elastase, may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation.
Cathepsin G is a 26kD protease.
Cathepsin G isa member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes.
The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation.
Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CTSG.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Ile21-Leu255 of human CTSG, fused to two N-terminal Tags, His-Tag and GST-tag, expressed in E. coli.
