The granulocyte macrophage colony-stimulating factor receptor is a receptor for granulocyte macrophage colony-stimulating factor, which stimulates the production of white blood cells.
The receptor is normally located on myeloblast, mature neutrophil, but not on any erythroid or megakaryocytic lineage cells
The granulocyte macrophage colony-stimulating factor receptor is a heterodimer composed of at least two different subunits; an alpha chain, and a Beta chain which is also present in the receptors for IL-3 and IL-5.
The alpha subunit contains a binding site for granulocyte macrophage colony-stimulating factor.
The Beta chain is involved in signal transduction.
Association of the alpha and Beta subunits results in receptor activation.
Applications:Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry: 5-20ug/mlImmunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher..
Storage and Stability:May be stored at 4°C.
for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.01% sarcosyl, 1mM DTT, 5% trehalose, Proclin300.
Specificity：Recognizes human CSF2Ra.
Isotype：IgG
Calc Applications Abbrev：IC IHC IP WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Arg28-Pro112 of human CSF2Ra, expressed in E. coli.
