C-reactive proteinis a liver-derived pattern recognition molecule that is increased in inflammatory states.
It rapidly increases withinhours after tissue injury, and it is suggested that it is part of the innate immune system and contributes to host defense.
Since cardiovascular disease is at least in part an inflammatory process, CRP has been investigated in the context of arteriosclerosis and subsequent vascular disorders.
Based on multiple epidemiological and intervention studies, minor CRP elevation has been shown to be associated with future major cardiovascular risk.CRP is known for several decades as a nonspecific inflammation marker.
High CRP levels are detected in human blood during bacterial, viral and other infections, as well as in noninfectious diseases such as rheumatic disorders and malignancies.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：chicken
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes chicken CRP.
Isotype：IgY
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Ch
Immunogen：Recombinant protein corresponding to Gln20-Ala227 of chicken CRP, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
