The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation.
It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein.
It was shown to be approximately 4.6 kb long and divided into 4 exons in a structure common to other members of the family of serum and cellular retinoid-binding proteins.
The chromosomal location of the Crabp-2 locus was determined by interspecific backcross analysis using progeny derived from matings of C57BL/6J and M.
spretus.
Mapping results indicated that the gene is located on mouse chromosome 2 linked to muscle nicotinic acetylcholine receptor alpha-chain (Acra) and catalase-1 (Cas-1).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CRABP2.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Met1-Glu138 of human CRABP2, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
