CRABP1 is a number of specific carrier proteins for members of the vitamin A family have been discovered.
Cellular retinoic acid-binding protein is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes.
CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid.
CRABP1 is constitutively expressed and is believed to have different functions in the cell than the related CRABP2.
Six such proteins have been well characterized: serum retinol-binding protein; cellular retinol-binding protein (CRBP); cellular retinoic acid-binding protein; cellular retinol-binding protein, unique to visual tissue; interphotoreceptor retinol-binding protein, also unique to visual tissue; and cellular retinol-binding protein, type II (CRBP2), present in small intestine.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CRABP1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Pro2-Glu137 of human CRABP1, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
