84-4412-40　COVA1 (Cytosolic Ovarian Carcinoma Antigen 1, APK1, tNOX, ENOX2, Ecto-NOX Disulfide-Thiol Exchanger 2, Tumor-associated hydroquinone oxidase, Hydroquinone [NADH] oxidase, Protein disulfide-thiol oxidoreductase) 200ul　362647

特徴

• COVA1 is a growth-related cell surface protein.
• It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein.
• The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange.
• The two activities alternate with a period length of about 24 minutes.
• The encoded protein also displays prion-like properties.
• Two transcript variants encoding different isoforms have been found for this gene.The COVA1 protein contains 3 potential N-linked glycosylation sites and multiple potential phosphorylation sites.
• Northern blot analysis revealed expression of a major 3.8-kb transcript predominantly in heart, placenta, and skeletal muscle but also in lung, liver, kidney, and pancreas.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.