XVI collagenis a member of the FACIT collagen family (fibril-associated collagens with interrupted helices).
Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix.
High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.
The remaining collagens belong to the latter class with a common feature being the presence of imperfections in the gly-Xaa-Xaa repeating pattern.
Within the latter class, collagens type IX, XII, and XIV form a subgroup called the FACIT collagens (for 'fibril-associated collagens with interrupted triple helices').
These collagens are associated with type I or II collagen fibrils and play a role in interaction of these fibrils with other matrix components.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human COL16.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Val1434-Gly1604 of human COL16, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
