Contactin-associated protein-like 4 is a protein belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors.
This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains.
In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains.
CASPR4 was expressed at variable levels in all brain tissues examined, with highest expression in the subthalamic nucleus and substantia nigra.
In situ hybridization and immunohistochemical analyses revealed high expression of CASPR4 in specific neuronal subpopulations in the olfactory bulb, hippocampus, deep cerebellar nuclei, and substantia nigra.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CNTNAP4.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Asn706-Lys886 of human CNTNAP4, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
