Contactin-2 is a member of the immunoglobulin superfamily.
It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule.
It may play a role in the formation of axon connections in the developing nervous system.
It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
Functional studies in vitro of axonal surface glycoproteins suggest that they are involved in cell adhesion and in the promotion of neurite outgrowth.
One of these proteins, the rat transient axonal glycoprotein (Tag1), is expressed by restricted subsets of central and peripheral neurons during the initial phase of neurite outgrowth.
Tag1 belongs to the immunoglobulin superfamily.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human CNTN2.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Val604-Phe771 of human CNTN2, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.