84-4411-95　CLU (Clusterin, TRPM2, KUB1, CLI, APOJ, SGP2, AAG4, APO-J, SP-40, Apolipoprotein J, Complement Lysis Inhibitor, 40,Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2) 200ul　362603

特徴

• Clusterin (apolipoprotein J) is a 75 - 80kD disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis.
• This protein has several synonyms: dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI).
• This protein was first identified in 1988 in seminal fluid.In humans the gene is encoded on chromosome 8 (8p21) and is highly conserved between species (70-80% homology).It is expressed in most mammalian tissues and can be found in blood plasma, milk, urine, cerebrospinal fluid and semen.
• A number of proteins have been found to affect its expression including Egr-1, members from the AP-1 complex, HSF1/2, Cdx1/2 and B-Myb.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400Immunocytochemistry: 1:50-500Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- VMPFPLLE PFNFHDVFQP FYDMIHQAQQ AMDAHLQRTP YHFPTMEFTE NNDRTVCKEI RHNSTGCLRM KDQCEKCQEI LEVDCSASNP TQTLLRQQLN ASLQLAEKFS RLYDQLLQSY QQKMLNTSAL LKQLNEQFTW VSQLANLTQS DDQHYLQVFT VNSHNSDPSI PSGLTKVIVK LFNSFPITVT VPQEVSSPNF MENVAEKALQ QYRRKSQEE
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.