CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis.
By sequencing clones obtained from a size-fractionated immature myeloid leukemia cell line cDNA library, Nomura et al.
(1994) obtained a partial cDNA encoding CD302, which they called KIAA0022.
Northern blot analysis revealed variable expression of a 4.2-kb CD302 transcript in all tissues examined, with highest levels in lung, liver, ovary, and peripheral blood.
By 3-prime RACE analysis of DEC205 (LY75) in a Hodgkin and Reed-Sternberg (HRS) lymphoma cell line, Kato et al.
(2003) identified a cDNA encoding a fusion of DEC205 with CD302, which they called DCL1.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse CLEC13A.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Asp21-Val225 of mouse CLEC13A, fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
