84-4411-82　CLEC10A (C-Type Lectin Domain Family 10, Member A, CD301, CLEC10-A, CLECSF13, CLECSF14, Macrophage Lectin 2(Calcium Dependent), C-type lectin superfamily member 14, Macrophage lectin 2) 200ul　362589

特徴

• C-type lectin domain family 10, member A also known as CLEC10A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.
• Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response
• The encoded type 2 transmembrane protein may function as a cell surface antigen.
• Two transcript variants encoding distinct isoforms have been identified for this gene.Sequence analysis predicted that the 292aa type II transmembrane protein has a cytoplasmic domain with a tyr-glu-asn-phe (YENF) internalization signal, a transmembrane domain, a neck domain, and a C-type lectin domain containing a gln-pro-asp motif.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- RA TLDNTTSKIK AEFQSLDSRA DSFEKGISSL KVDVEDHRQE LQAGRDLSQK VTSLESTVEK REQALKTDLS DLTDHVQQLR KDLKALTCQL ANLKNNGSEV ACCPLHWTEH EGSCYWFSES EKSWPEADKY CRLENSHLVV VNSLEEQNFL QNRLANVVSW IGLTDQNGPW RWVDGTDFEK GFKNWAPLQP DNWFGHGLGG GED
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.