Calumenin (CALU) is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting.
Calumenin is a member of the EF-hand superfamily in the ER and Golgi apparatus named CERC.
CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55, and calumenin
The CALU gene encodes a deduced 315aa protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal.
The human and mouse CALU proteins are 98% identical.
CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CALU.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Lys20-Phe315 of human CALU fused to His-Tag and T7-tag at N-terminal expressed in E. coli
